As a component of the spliceosome, U1 small nuclear ribonucleoproteins (U1RNPs) play critical roles in RNA splicing, and recent studies have shown that U1RNPs could recruit long non-coding RNAs (lncRNAs) to chromatin which are involved in cancer development.However, the interplay of U1 snRNP, lncRNAs and downstream genes and signaling pathways are
Objective.The purpose of this article is to analyze the spectrum of issues developing by the academician of the Russian Academy of Sciences and of the Russian Academy of Education A.L.Zhuravlev himself and to consider the questions elaborating under his guidance – with his co-workers and students in different periods of his scientific work; t
In this review, the Paediatric Assembly of the European Respiratory Society (ERS) presents a summary of the highlights and most relevant findings in the field of paediatric respiratory medicine presented at the virtual ERS International Congress 2020.Early Career Members of the ERS and Chairs of the different Groups comprising the Paediatric Assemb
Background: Sweating plays a key role in skin homeostasis, including antimicrobial and moisturizing effects, and regulation of skin surface pH.Impaired axon reflex-mediated (AXR) sweating has been observed in patients with atopic dermatitis (AD).However, the mechanism of such abnormal sudomotor axon reflex remains to be revealed.Methods: To investi
Excess choice has previously been shown to have detrimental effects on decisions about consumer products.As the number of options increases, people are more likely to put off making an active choice (i.e., defer) and show less satisfaction with any purchase actually made.We extend this line of enquiry to choosing a charitable organisation to volunt